Molecular Formula | C12H20NNaO4S |
Molar Mass | 297.34 |
Solubility | Soluble in water |
Appearance | White crystalline powder. |
BRN | 5689521 |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Sensitive | Sensitive to light |
MDL | MFCD00040641 |
Use | Chromogenic reagent for spectrophotometric determination of catalase. Only for quantitative determination of the concentration of uric acid (UA) in human serum, plasma or urine. Good water solubility, high sensitivity and stability. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3 |
HS Code | 29214200 |
Biological activity | TOOS is a highly water-soluble aniline derivative, widely used in diagnosis and biological experiments. |
use | developer for catalase spectrophotometric determination. Only for quantitative determination of the concentration of uric acid (UA) in human serum, plasma or urine. Good water solubility, high sensitivity and strong stability. cholesterol colorimetric determination; water-soluble reagent, used for catalase photometric determination water-soluble reagent, used for enzymatic photometric determination of hydrogen peroxide. the new Trinder's reagent is a highly water-soluble aniline derivative, which is widely used in diagnostic testing and biochemical testing. It has several advantages over conventional chromogenic reagents in colorimetric determination of hydrogen peroxide activity. The new Trinder's reagent is stable enough to be used in both solutions and test line detection systems. In the presence of hydrogen peroxide and peroxidase, the new Trinder's reagent forms a very stable purple or blue dye during the oxidative coupling reaction with 4-aminoantipyrine (4-AA) or 3-methylbenzothiazole sulfone hydrazone (MBTH). The molar absorbance of the dye coupled with MBTH was 1.5-2 times higher than that of the dye coupled with 4-AA; however, 4-AA solution was more stable than MBTH solution. The substrate is enzymatically oxidized by its oxidase to produce hydrogen peroxide. The concentration of this hydrogen peroxide corresponds to the substrate concentration. Therefore, the amount of substrate can be determined by the color development of the oxidative coupling reaction. Glucose, alcohol, acyl-CoA and cholesterol can be used to detect those substrates coupled with new Trinder's reagents and 4-AA. There are 10 new Trinder's reagents. Among the new Trinder's reagents, TOOS is the most commonly used. However, for specific substrates, testing different kinds of new Trinder's reagents is necessary to develop the best detection system. a water-soluble reagent for the determination of hydrogen peroxide by enzyme spectrophotometry. |